Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | SLC29A1 | Q99808 | 15/20 | 0.52 |
| ▸ | STAT6 | P42226 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886934 | 0.86 | SLC29A1 (0.51) | TP53SMN1; SMN2SLC29A1STAT6PDE4A | |
| SCHEMBL6885472 | 0.85 | SLC29A1 (0.52) | SMN1; SMN2SLC29A1STAT6 | |
| SCHEMBL672035 | 0.83 | SMN1; SMN2 (0.77) | TP53SMN1; SMN2SLC29A1STAT6 | |
| SCHEMBL19488384 | 0.83 | SMN1; SMN2 (0.77) | TP53SMN1; SMN2SLC29A1STAT6 | |
| SCHEMBL240981 | 0.83 | SMN1; SMN2 (0.77) | TP53SMN1; SMN2SLC29A1STAT6 | |
| SCHEMBL672036 | 0.83 | SMN1; SMN2 (0.77) | TP53SMN1; SMN2SLC29A1STAT6 | |
| SCHEMBL7134319 | 0.83 | SMN1; SMN2 (0.77) | TP53SMN1; SMN2SLC29A1STAT6 | |
| SCHEMBL30089484 | 0.83 | SMN1; SMN2 (0.77) | TP53SMN1; SMN2SLC29A1STAT6 | |
| SCHEMBL2580672 | 0.81 | SMN1; SMN2 (0.72) | TP53SMN1; SMN2SLC29A1STAT6 | |
| SCHEMBL2579342 | 0.79 | SMN1; SMN2 (0.38) | TP53SMN1; SMN2SLC29A1STAT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411954-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | Pharmasset Limited (BB) | 2004-04-28 | — | — | EP | disclosed |
| WO-2002032920-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | PHARMASSET LIMITED (BB) | 2002-04-25 | — | — | WO | disclosed |