SCHEMBL672035

SCHEMBL672035

CSc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.77
TP53 P04637 1/20 0.77
SLC29A1 Q99808 15/20 0.71
STAT6 P42226 2/20 0.69
DPP4 P27487 1/20 0.69
MEN1 O00255 1/20 0.69
SLC28A1 O00337 1/20 0.69
MAP3K7 O43318 1/20 0.69
SLC28A2 O43868 1/20 0.69
GAPDH P04406 1/20 0.69
ADORA3 P0DMS8 1/20 0.69
MAPK1 P28482 1/20 0.69
ADORA2A P29274 1/20 0.69
ADORA2B P29275 1/20 0.69
ADORA1 P30542 1/20 0.69
PI4KA P42356 1/20 0.69
KMT2A Q03164 1/20 0.69
PI4K2B Q8TCG2 1/20 0.69
DOT1L Q8TEK3 1/20 0.69
PI4K2A Q9BTU6 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL672036 1.00 SMN1; SMN2 (0.77) SMN1; SMN2TP53SLC29A1STAT6DPP4
SCHEMBL7134319 1.00 SMN1; SMN2 (0.77) SMN1; SMN2TP53SLC29A1STAT6DPP4
SCHEMBL30089484 1.00 SMN1; SMN2 (0.77) SMN1; SMN2TP53SLC29A1STAT6DPP4
SCHEMBL19488384 1.00 SMN1; SMN2 (0.77) SMN1; SMN2TP53SLC29A1STAT6DPP4
SCHEMBL240981 1.00 SMN1; SMN2 (0.77) SMN1; SMN2TP53SLC29A1STAT6DPP4
SCHEMBL26294910 0.91 SMN1; SMN2 (0.67) SMN1; SMN2TP53SLC29A1STAT6DPP4
SCHEMBL8500982 0.90 SLC29A1 (0.78) SMN1; SMN2SLC29A1STAT6DPP4MEN1
SCHEMBL2580672 0.90 SMN1; SMN2 (0.72) SMN1; SMN2TP53SLC29A1STAT6DPP4
SCHEMBL9350374 0.89 SLC29A1 (0.74) SMN1; SMN2SLC29A1STAT6DPP4MEN1
SCHEMBL9347373 0.89 SLC29A1 (0.74) SMN1; SMN2SLC29A1STAT6DPP4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 773 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119619828-A Instrument capable of realizing excitation test of synchronous motor in explosion-proof area 中国石油天然气股份有限公司 2025-03-14 CN claimed
WO-2024182811-A1 COMPOSITIONS AND METHODS FOR TREATING UTERINE LEIOMYOMAS UNIVERSITY OF SOUTH FLORIDA (US) 2024-09-06 WO claimed
US-20240024243-A1 Fine Dry Particulate Adenosine Compositions and Topical Formulations Including the Same LABORATORY SKIN CARE, INC. 2024-01-25 US claimed
US-20230346820-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF SARS-COV-2 THE SCRIPPS RESEARCH INSTITUTE 2023-11-02 US claimed
WO-2022232518-A1 CALXININ COMPOSITIONS AND METHOD FOR TREATING VIRAL INFECTIONS UNM RAINFOREST INNOVATIONS (US) 2022-11-03 WO claimed
US-20220273689-A1 POTENTIATION OF ANTIVIRAL NUCLEOBASES AS RNA VIRUS THERAPY REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2022-09-01 US claimed
US-20220002737-A1 ARTIFICIAL NUCLEIC ACID MOLECULES FOR IMPROVED PROTEIN EXPRESSION CUREVAC AG (DE) 2022-01-06 US claimed
US-20210379087-A1 COMPOSITIONS FOR THE ELIMINATION OF SENESCENT CELLS MEDIZINISCHE UNIVERSITÄT WIEN (AT) 2021-12-09 US claimed
CN-113347969-A Composition for eliminating senescent cells 维也纳自然资源与生命科学大学 2021-09-03 CN claimed
US-11021497-B2 Compositions and methods for synthesis of phosphorylated molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-06-01 US claimed
US-20030008841-A1 Anti-HCV nucleoside derivatives F. HOFFMAN-LA ROCHE, A SWISS COMPANY (CH) 2003-01-09 US claimed
WO-2002045720-A1 TREATMENT OF CANCER BY REDUCTION OF INTRACELLULAR ENERGY AND PYRIMIDINES SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2002-06-13 WO claimed
US-20020044919-A1 Combinations and methods for treating neoplasms YU, BAOFA 2002-04-18 US claimed
US-6355623-B2 DETERMINING THE LEVEL OF 6-THIOGUANINE METABOLITE WHEREIN A LEVEL OF 6-THIOGUANINE LESS THAN ABOUT 230 PMOL PER 8 X 108 RED BLOOD CELLS INDICATES A DRUG INCREASE; A LEVEL OF 400PMOL INDICATES A DECREASE; NONTOXIC HOPITAL-SAINTE-JUSTINE (CA) 2002-03-12 US claimed
EP-1171138-A2 USE OF 6-METHYLMERCAPTOPURINE RIBOSIDE IN OPHTHALMOLOGIC COMPOSITIONS Zoppetti, Giorgio (IT) 2002-01-16 EP claimed
WO-2001052868-A1 COMBINATIONS FOR TREATING NEOPLASMS YU BAOFA (US) 2001-07-26 WO claimed
WO-2000061122-A2 USE OF 6-METHYLMERCAPTOPURINE RIBOSIDE IN OPHTHALMOLOGIC COMPOSITIONS ZOPPETTI GIORGIO (IT) 2000-10-19 WO claimed
EP-0831855-A1 NUCLEOTIDE ANALOGUES FOR TOPICAL TREATMENT OF PROLIFERATIVE DISEASE OF THE SKIN HOSTETLER, Karl Y. (US) 1998-04-01 EP claimed
WO-1996040166-A1 NUCLEOTIDE ANALOGUES FOR TOPICAL TREATMENT OF PROLIFERATIVE DISEASE OF THE SKIN HOSTETLER KARL Y (US) 1996-12-19 WO claimed
US-4088756-A TREATING PSORIASIS, DERMATITIS WITH ADRENERGIC AGENTS AND HYPOGLYCEMIC AGENTS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1978-05-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220273689-A1 POTENTIATION OF ANTIVIRAL NUCLEOBASES AS RNA VIRUS THERAPY NSUN3, NSUN2, RNMT SMN1; SMN2 817/4885TP53 1942/4885SLC29A1 17/4885
US-20030008841-A1 Anti-HCV nucleoside derivatives PNP, HAVCR2, NUDT14 SMN1; SMN2 4281/4885TP53 3695/4885SLC29A1 18/4885
US-20220002737-A1 ARTIFICIAL NUCLEIC ACID MOLECULES FOR IMPROVED PROTEIN EXPRESSION CPSF6, CPSF1, RNMT SMN1; SMN2 2664/4885TP53 237/4885SLC29A1 1623/4885
US-11021497-B2 Compositions and methods for synthesis of phosphorylated molecules PIK3CA, CHAMP1, TYMP SMN1; SMN2 3259/4885TP53 1059/4885SLC29A1 498/4885
US-20230346820-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF SARS-COV-2 ACE2, SARS1, ACE SMN1; SMN2 2055/4885TP53 2487/4885SLC29A1 3931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.