Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 6/20 | 0.39 |
| ▸ | ACACA | Q13085 | 5/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463002 | 0.91 | MCHR1 (0.45) | MCHR1ADRA2AACACBACACANPY5R | |
| SCHEMBL6463001 | 0.91 | MCHR1 (0.45) | MCHR1ADRA2AACACBACACANPY5R | |
| SCHEMBL6877314 | 0.90 | MCHR1 (0.47) | MCHR1ADRA2AALDH1A1RXFP1MEN1 | |
| SCHEMBL4034150 | 0.85 | MCHR1 (0.57) | MCHR1ADRA2ANPY5R | |
| SCHEMBL4034147 | 0.85 | MCHR1 (0.57) | MCHR1ADRA2ANPY5R | |
| SCHEMBL6872666 | 0.83 | MCHR1 (0.43) | MCHR1ADRA2AVCPHTR2AHTR4 | |
| SCHEMBL6872664 | 0.83 | MCHR1 (0.43) | MCHR1ADRA2AVCPHTR2AHTR4 | |
| SCHEMBL6458468 | 0.83 | BCHE (0.46) | MCHR1ADRA2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6458481 | 0.83 | BCHE (0.46) | MCHR1ADRA2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6458474 | 0.83 | BCHE (0.46) | MCHR1ADRA2AALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |