Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 3/20 | 0.44 |
| ▸ | CDK8 | P49336 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6880682 | 1.00 | CCNC (0.44) | CCNCCDK8HTTMCHR1ADRA2A | |
| SCHEMBL6880615 | 0.89 | CCNC (0.47) | CCNCCDK8MCHR1ADRA2AHRH1 | |
| SCHEMBL6880610 | 0.89 | CCNC (0.47) | CCNCCDK8MCHR1ADRA2AHRH1 | |
| SCHEMBL6867810 | 0.88 | HTT (0.47) | HTTMCHR1ADRA2AHRH1ADRA1A | |
| SCHEMBL6867813 | 0.88 | HTT (0.47) | HTTMCHR1ADRA2AHRH1ADRA1A | |
| SCHEMBL6458020 | 0.87 | HTT (0.47) | HTTMCHR1ADRA2AHRH1ADRA1A | |
| SCHEMBL6458011 | 0.87 | HTT (0.47) | HTTMCHR1ADRA2AHRH1ADRA1A | |
| SCHEMBL6878023 | 0.87 | EPHX2 (0.45) | CCNCCDK8MCHR1ADRA2AHRH1 | |
| SCHEMBL6878016 | 0.87 | EPHX2 (0.45) | CCNCCDK8MCHR1ADRA2AHRH1 | |
| SCHEMBL6867462 | 0.81 | MCHR1 (0.45) | CCNCCDK8MCHR1ADRA2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |