Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.39 |
| ▸ | MELK | Q14680 | 3/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852362 | 0.80 | CYP2C9 (0.49) | CYP2C9CYP2C19CYP2D6CYP19A1PORCN | |
| SCHEMBL6881941 | 0.75 | ADRB2 (0.44) | CYP2C9CYP2C19MELKCYP2A6CYP3A4 | |
| SCHEMBL6850780 | 0.74 | CYP2D6 (0.49) | CYP2C9CYP2C19CYP2D6CYP19A1PORCN | |
| SCHEMBL7108097 | 0.73 | CYP2D6 (0.43) | CYP2C9CYP2C19CYP2D6CYP19A1PORCN | |
| SCHEMBL6852370 | 0.73 | CYP2D6 (0.43) | CYP2C9CYP2C19CYP2D6CYP19A1PORCN | |
| SCHEMBL6875995 | 0.73 | CYP2D6 (0.51) | CYP2C9CYP2C19CYP2D6CYP19A1PIK3CD | |
| SCHEMBL11541937 | 0.73 | CYP2D6 (0.60) | CYP2C9CYP2C19CYP2D6CYP19A1PIK3CD | |
| SCHEMBL6852505 | 0.71 | CYP2D6 (0.45) | CYP2C9CYP2C19CYP2D6CYP19A1PORCN | |
| SCHEMBL6881744 | 0.71 | CYP2D6 (0.53) | CYP2C9CYP2C19CYP2D6CYP19A1PORCN | |
| SCHEMBL6276326 | 0.71 | CYP2D6 (0.51) | CYP2C9CYP2C19CYP2D6CYP19A1PORCN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |
| US-20030220272-A1 | 6-O-acyl ketolide antibacterials | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220272-A1 | 6-O-acyl ketolide antibacterials | Q6ZSR9, ACSL6, RPS4Y1 | CYP2C9 956/4885CYP2C19 1857/4885CYP2D6 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.