SCHEMBL6881473

SCHEMBL6881473

CC1(C)O[C@H]2[C@H](n3cc(I)c4c(Cl)ncnc43)OC(C)(C)[C@H]2O1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADK P55263 20/20 0.53
SLC29A1 Q99808 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6235668 0.82 ADK (0.65) ADKSLC29A1
SCHEMBL6872237 0.80 ADK (0.51) ADKSLC29A1
SCHEMBL68579 0.79 ADK (0.56) ADKSLC29A1
SCHEMBL67029 0.78 ADK (0.67) ADKSLC29A1
SCHEMBL60684 0.78 ADK (0.67) ADKSLC29A1
SCHEMBL90990 0.78 ADK (0.67) ADKSLC29A1
SCHEMBL19343826 0.78 ADK (0.52) ADKSLC29A1
SCHEMBL27195450 0.77 ADK (0.45) ADKSLC29A1
SCHEMBL31022853 0.77 ADK (0.45) ADKSLC29A1
SCHEMBL18589195 0.76 ADK (0.47) ADKSLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0832091-B1 C-4' MODIFIED ADENOSINE KINASE INHIBITORS GENSIA SICOR INC (US) 2004-01-14 EP disclosed