Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1941485 | 0.94 | REN (0.79) | REN | |
| SCHEMBL8260014 | 0.93 | REN (1.00) | REN | |
| SCHEMBL29413121 | 0.93 | REN (1.00) | REN | |
| SCHEMBL1941953 | 0.93 | REN (1.00) | REN | |
| SCHEMBL1941950 | 0.93 | REN (1.00) | REN | |
| SCHEMBL1943146 | 0.93 | REN (1.00) | REN | |
| SCHEMBL1940722 | 0.93 | REN (1.00) | REN | |
| SCHEMBL1943046 | 0.93 | REN (1.00) | REN | |
| SCHEMBL1943047 | 0.93 | REN (1.00) | REN | |
| SCHEMBL1941924 | 0.93 | REN (1.00) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673931-B2 | (4-(4-(3-(2-METHOXY-BENZYLOXY)-PROPOXY)-PHENYL)-5-(4-METHOXY -NAPHTHALEN-2-YLMETHOXY)-PIPERIDIN-3-YL)-METHANOL FOR EXAMPLE; USE TREATING RESTENOSIS, GLAUCOMA, CARDIAC AND KIDNEY INSUFFICIENCY | HOFFMAN-LA ROCHE INC. | 2004-01-06 | — | — | US | disclosed |