Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 11/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688053 | 0.92 | PTGER3 (0.43) | PTGER3CNR2SLC22A12TP53MAPT | |
| SCHEMBL686846 | 0.92 | PTGER3 (0.41) | PTGER3CNR2SLC22A12CYP26A1ITGB1 | |
| SCHEMBL688442 | 0.92 | PTGER3 (0.42) | PTGER3CNR2SLC22A12CYP26A1TP53 | |
| SCHEMBL29371834 | 0.91 | PTGER3 (0.44) | PTGER3CNR2SLC22A12 | |
| SCHEMBL688284 | 0.91 | PTGER3 (0.43) | PTGER3CNR2SLC22A12CYP26A1ITGB1 | |
| SCHEMBL686896 | 0.91 | PTGER3 (0.44) | PTGER3CNR2SLC22A12 | |
| SCHEMBL688233 | 0.91 | PTGER3 (0.43) | PTGER3CNR2SLC22A12CYP26A1TP53 | |
| SCHEMBL688343 | 0.91 | PTGER3 (0.43) | PTGER3CNR2SLC22A12TP53MAPT | |
| SCHEMBL687923 | 0.91 | PTGER3 (0.41) | PTGER3CNR2SLC22A12ITGB1ITGA4 | |
| SCHEMBL687045 | 0.89 | PTGER3 (0.42) | PTGER3CNR2SLC22A12CYP26A1ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |