Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284612 | 0.77 | — | — | |
| SCHEMBL4440529 | 0.67 | — | — | |
| SCHEMBL95982 | 0.67 | TSHR (1.00) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL17644802 | 0.66 | — | — | |
| SCHEMBL20163989 | 0.66 | — | — | |
| SCHEMBL2611585 | 0.66 | TSHR (0.72) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL9257453 | 0.66 | — | — | |
| Acetic Acid SCHEMBL6932730 | 0.65 | TSHR (0.81) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL8603684 | 0.65 | TSHR (0.62) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL720967 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2080063-B1 | METHOD AND FORMULATION FOR REINFORCING ELASTOMERS | COOPER TIRE & RUBBER CO (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-2080063-A2 | METHOD AND FORMULATION FOR REINFORCING ELASTOMERS | Cooper Tire & Rubber Company (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008057533-A2 | METHOD AND FORMULATION FOR REINFORCING ELASTOMERS | COOPER TIRE & RUBBER COMPANY (US) | 2008-05-15 | — | — | WO | disclosed |