Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18854912 | 0.91 | KMT2A (0.66) | ALDH1A1KDM4ELMNAGAAKMT2A | |
| SCHEMBL6232255 | 0.88 | ACACB (0.56) | ALDH1A1KDM4ELMNAGAAKMT2A | |
| SCHEMBL6488791 | 0.84 | KMT2A (0.58) | ALDH1A1KDM4ELMNAGAAKMT2A | |
| SCHEMBL6481851 | 0.82 | KMT2A (0.59) | ALDH1A1KDM4ELMNAGAAKMT2A | |
| SCHEMBL6481517 | 0.82 | KMT2A (0.53) | ALDH1A1KDM4ELMNAGAAKMT2A | |
| SCHEMBL6480776 | 0.81 | KMT2A (0.53) | ALDH1A1KDM4ELMNAGAAKMT2A | |
| SCHEMBL6491894 | 0.81 | KMT2A (0.52) | ALDH1A1KDM4ELMNAGAAKMT2A | |
| SCHEMBL6408739 | 0.81 | KMT2A (0.54) | ALDH1A1KDM4ELMNAGAAKMT2A | |
| SCHEMBL10062332 | 0.81 | KMT2A (0.61) | ALDH1A1KDM4ELMNAGAAKMT2A | |
| SCHEMBL5853027 | 0.80 | KDM4E (0.59) | ALDH1A1KDM4ELMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706722-B2 | IN PARTICULAR FOR TREATING TUMORS. | ZENTARIS AG (DE) | 2004-03-16 | — | — | US | disclosed |
| US-20020132821-A1 | Novel heteroaryl derivatives and their use as medicaments | ZENTARIS GMBH (DE) | 2002-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020132821-A1 | Novel heteroaryl derivatives and their use as medicaments | ABCB1, ABCB11, FANCD2 | ALDH1A1 173/4885KDM4E 4409/4885LMNA 1922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.