⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25358655 | 0.76 | — | — | |
| SCHEMBL25358654 | 0.76 | — | — | |
| SCHEMBL11569343 | 0.71 | — | — | |
| SCHEMBL15465767 | 0.67 | — | — | |
| SCHEMBL30936078 | 0.65 | — | — | |
| SCHEMBL12377031 | 0.65 | — | — | |
| SCHEMBL289192 | 0.60 | — | — | |
| SCHEMBL15464856 | 0.60 | — | — | |
| SCHEMBL7513835 | 0.55 | — | — | |
| SCHEMBL2885710 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063323-A | Beta-halogenated nitrate compound and preparation method and application thereof | 上海师范大学 | 2024-05-24 | — | — | CN | disclosed |
| WO-2023168827-A1 | SYNTHESIS METHOD FOR PAXLOVID INTERMEDIATE | 杭州国瑞生物科技有限公司 | 2023-09-14 | — | — | WO | disclosed |
| WO-2023122754-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING GB13, GB22 AND HIMGALINE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-06-29 | — | — | WO | disclosed |
| US-6825211-B1 | GLUTAMATE RECEPTORS PLAY A ROLE IN NUMEROUS NEUROLOGICAL, NEURODEGENERATIVE, PSYCHIATRIC, AND PSYCHOLOGICAL DISORDERS | GEORGETOWN UNIVERSITY | 2004-11-30 | — | — | US | disclosed |
| US-6610743-B2 | Central nervous system disorders | GEORGETOWN UNIVERSITY | 2003-08-26 | — | — | US | disclosed |
| US-20020165200-A1 | Bicyclic metabotropic glutamate receptor ligands | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-11-07 | — | — | US | disclosed |
| US-6376532-B2 | NEUROTRANSMITTER | GEORGETOWN UNIVERSITY | 2002-04-23 | — | — | US | disclosed |
| US-20010018429-A1 | Neurotransmitter | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2001-08-30 | — | — | US | disclosed |
| US-6204292-B1 | TREATMENT OF NEUROLOGICAL, NEURODEGENERATIVE, PSYCHIATRIC AND PSYCHOLOGICAL DISORDERS. | GEORGETOWN UNIVERSITY | 2001-03-20 | — | — | US | disclosed |
| EP-1000015-A1 | BICYCLIC METABOTROPIC GLUTAMATE RECEPTOR LIGANDS | GEORGETOWN UNIVERSITY (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999003822-A9 | BICYCLIC METABOTROPIC GLUTAMATE RECEPTOR LIGANDS | UNIV GEORGETOWN (US) | 1999-04-29 | — | — | WO | disclosed |
| WO-1999003822-A1 | BICYCLIC METABOTROPIC GLUTAMATE RECEPTOR LIGANDS | GEORGETOWN UNIVERSITY (US) | 1999-01-28 | — | — | WO | disclosed |