Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29109603 | 1.00 | PPM1B (0.38) | PPM1BPTPN1PPP1CCMAPTPKM | |
| SCHEMBL4472058 | 1.00 | PPM1B (0.38) | PPM1BPTPN1PPP1CCMAPTPKM | |
| SCHEMBL6882185 | 1.00 | PPM1B (0.38) | PPM1BPTPN1PPP1CCMAPTPKM | |
| SCHEMBL6882050 | 1.00 | PPM1B (0.38) | PPM1BPTPN1PPP1CCMAPTPKM | |
| SCHEMBL23555977 | 0.82 | ALDH1A1 (0.40) | PPM1BPTPN1PPP1CCMAPTALDH1A1 | |
| SCHEMBL24524725 | 0.82 | ALDH1A1 (0.40) | PPM1BPTPN1PPP1CCMAPTALDH1A1 | |
| SCHEMBL23555976 | 0.82 | ALDH1A1 (0.40) | PPM1BPTPN1PPP1CCMAPTALDH1A1 | |
| SCHEMBL19973666 | 0.81 | SPHK1 (0.39) | PPM1BPTPN1PPP1CCMAPTPKM | |
| SCHEMBL116264 | 0.81 | SPHK1 (0.39) | PPM1BPTPN1PPP1CCMAPTPKM | |
| SCHEMBL8427865 | 0.81 | SPHK1 (0.39) | PPM1BPTPN1PPP1CCMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091407-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLP (US) | 2011-07-28 | — | — | WO | disclosed |