Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 11/20 | 0.48 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092572 | 0.87 | HTT (0.49) | DRD4HTTGRIN1GRIN2BKDM4E | |
| SCHEMBL6880434 | 0.83 | DRD4 (0.47) | DRD4HTTDRD2GRIN1GRIN2B | |
| SCHEMBL6880423 | 0.81 | DRD4 (0.54) | DRD4HTTDRD2GRIN1GRIN2B | |
| SCHEMBL6880280 | 0.79 | HPGD (0.67) | DRD4HTTDRD2KDM4EALDH1A1 | |
| SCHEMBL6881533 | 0.78 | DRD4 (0.49) | DRD4HTTDRD2PDE10AKDM4E | |
| SCHEMBL6881767 | 0.78 | DRD4 (0.45) | DRD4HTTDRD2GRIN1GRIN2B | |
| SCHEMBL6881731 | 0.77 | DRD4 (0.52) | DRD4HTTDRD2KDM4EALDH1A1 | |
| SCHEMBL6878954 | 0.77 | DRD4 (0.52) | DRD4HTTDRD2GRIN1GRIN2B | |
| SCHEMBL6881772 | 0.77 | DRD4 (0.48) | DRD4HTTDRD2KDM4EALDH1A1 | |
| SCHEMBL6883746 | 0.77 | DRD4 (0.51) | DRD4HTTDRD2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040166137-A1 | Hetero-substituted benzimidazole compounds and antiviral uses thereof | TRIMERIS, INC. | 2004-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040166137-A1 | Hetero-substituted benzimidazole compounds and antiviral uses thereof | MAVS, TIMM13, TIMM10 | DRD4 1550/4885SLC40A1 3431/4885HTT 1686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.