SCHEMBL6883007

SCHEMBL6883007

CC1OC2C(O)[C@@H]3OC(c4ccccc4)OCC3O[C@@H]2O1

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.62
▸ MEN1 O00255 3/20 0.62
▸ L3MBTL1 Q9Y468 3/20 0.56
▸ ALDH1A1 P00352 4/20 0.41
▸ CYP2C19 P33261 1/20 0.39
▸ MAPT P10636 3/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ LMNA P02545 2/20 0.34
▸ ATM Q13315 2/20 0.34
▸ MITF O75030 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ PKM P14618 1/20 0.34
▸ TSHR P16473 1/20 0.33
▸ PDCD1 Q15116 2/20 0.32
▸ CD274 Q9NZQ7 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27586182 1.00 KMT2A (0.62) KMT2AMEN1L3MBTL1ALDH1A1CYP2C19
SCHEMBL17590137 1.00 KMT2A (0.62) KMT2AMEN1L3MBTL1ALDH1A1CYP2C19
SCHEMBL12659164 1.00 KMT2A (0.62) KMT2AMEN1L3MBTL1ALDH1A1CYP2C19
SCHEMBL7150024 0.90 KMT2A (0.63) KMT2AMEN1L3MBTL1ALDH1A1CYP2C19
SCHEMBL17590134 0.87 KMT2A (0.50) KMT2AMEN1L3MBTL1ALDH1A1CYP2C19
SCHEMBL12659165 0.87 KMT2A (0.50) KMT2AMEN1L3MBTL1ALDH1A1CYP2C19
SCHEMBL29306273 0.87 KMT2A (0.60) KMT2AMEN1L3MBTL1ALDH1A1CYP2C19
SCHEMBL13380989 0.83 KMT2A (0.69) KMT2AMEN1L3MBTL1ALDH1A1CYP2C19
SCHEMBL13743115 0.83 KMT2A (0.69) KMT2AMEN1L3MBTL1ALDH1A1CYP2C19
SCHEMBL10238940 0.83 KMT2A (0.69) KMT2AMEN1L3MBTL1ALDH1A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8288515-B2 Process for preparing Fondaparinux sodium and intermediates useful in the synthesis thereof RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2012-10-16 — — US disclosed
US-20110105418-A1 PROCESS FOR PREPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2011-05-05 — — US disclosed
WO-2011014793-A9 PROCESS FOR PREPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2011-03-24 — — WO disclosed
WO-2011014793-A2 PROCESS FOR PREPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2011-02-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110105418-A1 PROCESS FOR PREPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF F11, TFPI, STS KMT2A 2999/4885MEN1 1877/4885L3MBTL1 4103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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