Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | NPC1 | O15118 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | LDLR | P01130 | 1/20 | 0.53 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2967236 | 0.84 | NPC1 (0.50) | RAB9AMAPTKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL12764365 | 0.79 | SMN1; SMN2 (0.58) | RAB9AMAPTKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL12764388 | 0.78 | SMN1; SMN2 (0.57) | RAB9AMAPTKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL12552711 | 0.77 | TDP1 (0.62) | RAB9AMAPTNPC1SMN1; SMN2KDM4E | |
| SCHEMBL6400541 | 0.76 | PLAU (0.59) | RAB9AMAPTKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL18470910 | 0.74 | RAB9A (1.00) | RAB9AMAPTKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL3142490 | 0.74 | RAB9A (1.00) | RAB9AMAPTKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL6483771 | 0.74 | MAPK14 (0.54) | RAB9AMAPTKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL1947842 | 0.73 | NPC1 (0.80) | RAB9AMAPTKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL14503774 | 0.73 | MAPT (0.58) | RAB9AMAPTKMT2ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6821965-B1 | IMPORTANT IN DISEASE OR MEDICAL CONDITIONS SUCH AS INFLAMMATION AND IMMUNOREGULATION | ASTERZENECA AB (SE) | 2004-11-23 | — | — | US | disclosed |