Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 12/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GALK1 | P51570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6043957 | 0.85 | HCAR3 (1.00) | HCAR3MAPTTP53RXFP1HPGD | |
| SCHEMBL6044131 | 0.82 | HCAR3 (1.00) | HCAR3MAPTTP53RXFP1GAA | |
| SCHEMBL6044013 | 0.82 | HCAR3 (1.00) | HCAR3MAPTTP53RXFP1HPGD | |
| SCHEMBL6044076 | 0.81 | HCAR3 (1.00) | HCAR3MAPTTP53RXFP1GAA | |
| SCHEMBL26576420 | 0.81 | HCAR3 (0.77) | HCAR3TP53RXFP1HPGDHCAR2 | |
| SCHEMBL29490305 | 0.73 | HCAR3 (0.78) | HCAR3TP53RXFP1HPGDHCAR2 | |
| SCHEMBL22862503 | 0.73 | HCAR3 (0.78) | HCAR3TP53RXFP1HPGDHCAR2 | |
| SCHEMBL2490016 | 0.72 | HCAR3 (0.60) | HCAR3HPGDHCAR2 | |
| SCHEMBL6688047 | 0.71 | HCAR3 (0.77) | HCAR3MAPTTP53RXFP1 | |
| SCHEMBL5921944 | 0.70 | HCAR3 (0.68) | HCAR3HPGDHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373191-A1 | ACYLATED INDANYL AMINES AND THEIR USE AS PHARMACEUTICALS | Aventis Pharma Deutschland GmbH (DE) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002064545-A1 | ACYLATED INDANYL AMINES AND THEIR USE AS PHARMACEUTICALS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-08-22 | — | — | WO | disclosed |