SCHEMBL6883371

SCHEMBL6883371

COC(=O)N(Cc1cc(Cl)cc(Cl)c1)[C@H]1C[C@@H](C2CC2)N(C(=O)O)c2ccc(C(F)(F)F)cc21

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6570553 1.00 CETP (0.57) CETP
SCHEMBL6359793 0.92 CETP (0.67) CETP
SCHEMBL5491860 0.92 CETP (0.67) CETP
SCHEMBL7229056 0.91 CETP (0.57) CETP
SCHEMBL7229060 0.91 CETP (0.57) CETP
SCHEMBL7229063 0.91 CETP (0.57) CETP
SCHEMBL6064627 0.90 CETP (0.60) CETP
SCHEMBL6184469 0.90 CETP (0.60) CETP
SCHEMBL992306 0.90 CETP (0.60) CETP
SCHEMBL6181944 0.87 CETP (0.67) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1404302-A1 PHARMACEUTICAL COMPOSITIONS OF ADSORBATES OF AMORPHOUS DRUG Pfizer Products Inc. (US) 2004-04-07 EP disclosed
WO-2003000235-A9 PHARMACEUTICAL COMPOSITIONS OF DISPERSIONS OF DRUGS AND NEUTRAL POLYMERS PFIZER PROD INC (US) 2003-12-24 WO disclosed
WO-2003000238-A1 PHARMACEUTICAL COMPOSITIONS OF ADSORBATES OF AMORPHOUS DRUG PFIZER PRODUCTS INC. (US) 2003-01-03 WO disclosed