Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 10/20 | 0.57 |
| ▸ | DCUN1D1 | Q96GG9 | 10/20 | 0.40 |
| ▸ | UBE2M | P61081 | 9/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7229063 | 1.00 | CETP (0.57) | CETPDCUN1D1UBE2M | |
| SCHEMBL7229056 | 1.00 | CETP (0.57) | CETPDCUN1D1UBE2M | |
| SCHEMBL6359793 | 0.93 | CETP (0.67) | CETP | |
| SCHEMBL5491860 | 0.93 | CETP (0.67) | CETP | |
| SCHEMBL6185653 | 0.91 | CETP (0.59) | CETP | |
| SCHEMBL6185656 | 0.91 | CETP (0.59) | CETP | |
| SCHEMBL6185650 | 0.91 | CETP (0.59) | CETP | |
| SCHEMBL6883371 | 0.91 | CETP (0.57) | CETP | |
| SCHEMBL6570553 | 0.91 | CETP (0.57) | CETP | |
| SCHEMBL6181939 | 0.86 | CETP (0.67) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586448-B1 | Cholesteryl ester transfer protein inhibitors used as antilipemic agents for prophylaxis of cardiovascular disorders | PFIZER INC. | 2003-07-01 | — | — | US | disclosed |