Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.46 |
| ▸ | ESRRA | P11474 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.43 |
| ▸ | PTPN12 | Q05209 | 2/20 | 0.43 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877633 | 1.00 | FDPS (0.46) | FDPSESRRAALDH1A1KMT2AMAPT | |
| SCHEMBL6882986 | 0.91 | FDPS (0.56) | FDPSALDH1A1KDM4EHTTHPGD | |
| SCHEMBL6882991 | 0.91 | FDPS (0.56) | FDPSALDH1A1KDM4EHTTHPGD | |
| SCHEMBL6875479 | 0.90 | FDPS (0.50) | FDPSESRRAALDH1A1KMT2AMAPT | |
| SCHEMBL6875471 | 0.90 | FDPS (0.50) | FDPSESRRAALDH1A1KMT2AMAPT | |
| SCHEMBL13934768 | 0.84 | FDPS (0.52) | FDPSALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL4416182 | 0.84 | FDPS (0.52) | FDPSALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL4416176 | 0.84 | FDPS (0.52) | FDPSALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL18936864 | 0.81 | FDPS (0.70) | FDPSKDM4EBCHEACHE | |
| SCHEMBL9952708 | 0.81 | FDPS (0.70) | FDPSKDM4EBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6833421-B1 | Compound | ROLIC AG (CH) | 2004-12-21 | — | — | US | disclosed |
| EP-1200494-B1 | COMPOUND | ROLIC AG (CH) | 2004-08-18 | — | — | EP | disclosed |
| EP-1200494-A1 | COMPOUND | Rolic AG (CH) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001007495-A1 | COMPOUND | ROLIC AG (CH) | 2001-02-01 | — | — | WO | disclosed |