Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | SCN4A | P35499 | 1/20 | 0.59 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.59 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885191 | 0.97 | KDM4E (0.68) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL75509 | 0.96 | KDM4E (0.67) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL6885051 | 0.94 | KDM4E (0.67) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL18767312 | 0.90 | MAOB (0.67) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL18767964 | 0.86 | SLC6A2 (0.59) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL22534020 | 0.85 | MAOB (0.60) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL22533895 | 0.84 | SCN4A (0.65) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL18768573 | 0.82 | SLC6A2 (0.66) | KDM4EHSD17B10HPGDDRD2HDAC3 | |
| SCHEMBL23458866 | 0.81 | NPC1 (0.47) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL29919245 | 0.81 | NPC1 (0.47) | KDM4EHSD17B10HPGDSCN4ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1460064-A1 | Indole-2-carboxamide derivatives useful as beta-2 agonists | Pfizer Limited (GB) | 2004-09-22 | — | — | EP | disclosed |