Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | SCN4A | P35499 | 1/20 | 0.57 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.57 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22534020 | 0.93 | MAOB (0.60) | MAOBKDM4EHSD17B10HPGDSCN4A | |
| SCHEMBL6885051 | 0.92 | KDM4E (0.67) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL6885191 | 0.90 | KDM4E (0.68) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL6883734 | 0.90 | KDM4E (0.68) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL75509 | 0.88 | KDM4E (0.67) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL18767964 | 0.84 | SLC6A2 (0.59) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL22533895 | 0.81 | SCN4A (0.65) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL21822116 | 0.80 | ITGB3 (0.57) | NAMPT | |
| SCHEMBL18768573 | 0.80 | SLC6A2 (0.66) | MAOBKDM4EHSD17B10HPGDDRD2 | |
| SCHEMBL30102648 | 0.80 | MAOB (0.60) | MAOBKDM4ESCN4ASCN9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066705-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE AGAINST STRESS GRANULES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2017-04-20 | — | — | WO | disclosed |