Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 6/20 | 0.71 |
| ▸ | MPI | P34949 | 8/20 | 0.51 |
| ▸ | PHOSPHO1 | Q8TCT1 | 8/20 | 0.51 |
| ▸ | PMM2 | O15305 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8373511 | 0.83 | G6PD (1.00) | G6PDMPIPHOSPHO1PMM2KDM4E | |
| SCHEMBL8371826 | 0.81 | G6PD (0.74) | G6PDMPIPHOSPHO1PMM2KDM4E | |
| SCHEMBL8373401 | 0.79 | G6PD (0.72) | G6PDMPIPHOSPHO1PMM2KDM4E | |
| SCHEMBL10872662 | 0.74 | G6PD (0.78) | G6PDMPIPHOSPHO1PMM2KDM4E | |
| SCHEMBL29530129 | 0.74 | MPI (0.65) | G6PDMPIPHOSPHO1PMM2ALDH1A1 | |
| SCHEMBL1901601 | 0.74 | MPI (0.65) | G6PDMPIPHOSPHO1PMM2ALDH1A1 | |
| SCHEMBL10877003 | 0.73 | PHOSPHO1 (0.68) | G6PDMPIPHOSPHO1PMM2KDM4E | |
| SCHEMBL8373535 | 0.72 | G6PD (0.74) | G6PDMPIPHOSPHO1PMM2KDM4E | |
| SCHEMBL18913001 | 0.72 | G6PD (0.74) | G6PDMPIPHOSPHO1PMM2KDM4E | |
| SCHEMBL8371843 | 0.72 | G6PD (0.62) | G6PDMPIPHOSPHO1PMM2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011062864-A2 | INHIBITORS OF NOX ENZYMES AND METHODS OF USE THEREOF | EMORY UNIVERSITY (US) | 2011-05-26 | — | — | WO | disclosed |