Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 9/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688643 | 0.98 | PTGER3 (0.41) | PTGER3CNR2CTSAMAPT | |
| SCHEMBL687127 | 0.94 | PTGER3 (0.42) | PTGER3CNR2CTSAMAPTP2RY14 | |
| SCHEMBL686663 | 0.92 | PTGER3 (0.44) | PTGER3CNR2CTSAMAPTP2RY14 | |
| SCHEMBL686806 | 0.89 | PTGER3 (0.45) | PTGER3CNR2CTSAMAPTP2RY14 | |
| SCHEMBL29371834 | 0.88 | PTGER3 (0.44) | PTGER3CNR2CTSAP2RY14 | |
| SCHEMBL686896 | 0.88 | PTGER3 (0.44) | PTGER3CNR2CTSAP2RY14 | |
| SCHEMBL688458 | 0.86 | PTGER3 (0.43) | PTGER3CNR2CTSAMAPT | |
| SCHEMBL686903 | 0.84 | SLC22A12 (0.40) | PTGER3CNR2MAPT | |
| SCHEMBL687778 | 0.83 | CNR2 (0.43) | PTGER3CNR2CTSA | |
| SCHEMBL688053 | 0.83 | PTGER3 (0.43) | PTGER3CNR2CTSAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |