Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5496855 | 1.00 | FKBP1A (0.53) | FKBP1AALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL5496862 | 1.00 | FKBP1A (0.53) | FKBP1AALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL5495836 | 0.94 | ACE (0.52) | FKBP1AALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL6877311 | 0.94 | ACE (0.52) | FKBP1AALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL5495829 | 0.94 | ACE (0.52) | FKBP1AALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL3742096 | 0.90 | FKBP1A (0.54) | FKBP1AALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8626274 | 0.89 | FKBP1A (0.56) | FKBP1AALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL683426 | 0.88 | FKBP1A (0.51) | FKBP1AALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL5492839 | 0.88 | FKBP1A (0.47) | FKBP1ASPHK1 | |
| SCHEMBL5497946 | 0.88 | FKBP1A (0.47) | FKBP1ASPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458680-A1 | PRODRUGS TO D-PROLINES | F. Hoffmann-La Roche AG (CH) | 2004-09-22 | — | — | EP | claimed |
| WO-2003051836-A1 | PRODRUGS TO D-PROLINES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-06-26 | — | — | WO | claimed |
| EP-1458680-A1 | PRODRUGS TO D-PROLINES | F. Hoffmann-La Roche AG (CH) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051836-A1 | PRODRUGS TO D-PROLINES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-06-26 | — | — | WO | disclosed |