Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31566277 | 1.00 | ALDH1A1 (0.43) | ALDH1A1TSHRTHRB | |
| SCHEMBL2956146 | 0.97 | — | — | |
| SCHEMBL16596 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRTHRB | |
| SCHEMBL217593 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRTHRB | |
| SCHEMBL165290 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRTHRB | |
| SCHEMBL9639226 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRTHRB | |
| SCHEMBL5839297 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRTHRB | |
| SCHEMBL987828 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRTHRB | |
| SCHEMBL989839 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRTHRB | |
| SCHEMBL9639301 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693520-A | Compounds with higher PKG (protein kinase G) inhibitory activity and preparation method of compounds | 天津键凯科技有限公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-104610233-B | Compound with higher protein kinase G inhibition activity and preparation method thereof | 天津键凯科技有限公司 | 2016-06-08 | — | — | CN | disclosed |
| EP-1490083-A1 | MICROGEL PARTICLES FOR THE DELIVERY OF BIOACTIVE MATERIALS | The Regents of the University of California (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003082316-A1 | MICROGEL PARTICLES FOR THE DELIVERY OF BIOACTIVE MATERIALS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-10-09 | — | — | WO | disclosed |
| EP-0341409-B1 | Platinum (II) complexes, their preparation and use as antitumour agents | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-12-29 | — | — | EP | disclosed |
| EP-0415939-A1 | PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOUR AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-03-13 | — | — | EP | disclosed |
| EP-0341409-A1 | Platinum (II) complexes, their preparation and use as antitumour agents | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1989-11-15 | — | — | EP | disclosed |
| WO-1989009218-A1 | PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOUR AGENTS | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-10-05 | — | — | WO | disclosed |