Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466362 | 0.83 | AR (0.69) | ARALDH1A1MAPTGAAPKM | |
| SCHEMBL6466732 | 0.81 | AR (0.66) | ARALDH1A1MAPTGAAPKM | |
| SCHEMBL16344540 | 0.79 | GAA (0.77) | ARALDH1A1MAPTGAAPKM | |
| SCHEMBL6469603 | 0.78 | AR (0.81) | ARALDH1A1MAPTGAAPKM | |
| SCHEMBL6466009 | 0.77 | AR (0.83) | ARALDH1A1MAPTGAAPKM | |
| SCHEMBL7701611 | 0.75 | MAPT (1.00) | ARALDH1A1MAPTGAAPKM | |
| SCHEMBL6469535 | 0.75 | AR (0.76) | ARALDH1A1MAPTGAAPKM | |
| SCHEMBL6464115 | 0.75 | AR (0.80) | ARALDH1A1MAPTGAAPKM | |
| SCHEMBL6468911 | 0.74 | AR (1.00) | ARALDH1A1MAPTGAAPKM | |
| SCHEMBL6468214 | 0.74 | AR (0.78) | ARALDH1A1MAPTGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |