Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | PKM | P14618 | 5/20 | 1.00 |
| ▸ | GAA | P10253 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 6/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.82 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803358 | 0.90 | MAPT (1.00) | MAPTPKMGAAALDH1A1LMNA | |
| SCHEMBL290852 | 0.88 | GAA (0.79) | MAPTPKMGAAALDH1A1LMNA | |
| SCHEMBL7699327 | 0.88 | ALDH1A1 (0.78) | MAPTPKMGAAALDH1A1LMNA | |
| SCHEMBL16344540 | 0.87 | GAA (0.77) | MAPTPKMGAAALDH1A1LMNA | |
| SCHEMBL14880137 | 0.85 | MAPT (0.74) | MAPTPKMGAAALDH1A1LMNA | |
| SCHEMBL7961660 | 0.84 | PLA2G2A (0.75) | MAPTPKMGAAALDH1A1LMNA | |
| SCHEMBL336671 | 0.84 | MAPT (0.73) | MAPTPKMGAAALDH1A1LMNA | |
| SCHEMBL16027079 | 0.82 | MAPT (0.70) | MAPTPKMGAAALDH1A1LMNA | |
| SCHEMBL805691 | 0.81 | MAPT (0.69) | MAPTPKMGAAALDH1A1LMNA | |
| SCHEMBL5437216 | 0.81 | PLA2G2A (0.82) | MAPTPKMGAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020478-A1 | N-BENZYLINDOLE-3-ACETIC ACID DERIVATIVES FOR USE IN THE TREATMENT OF DRUG RESISTAN CANCER | DUBLIN CITY UNIVERSITY (IE) | 2002-03-14 | — | — | WO | disclosed |