Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155990 | 0.86 | PPARA (0.42) | PPARABACE1KMT2AL3MBTL1 | |
| SCHEMBL6884350 | 0.80 | KMT2A (0.35) | PPARAFFAR1TBXAS1BACE1KMT2A | |
| SCHEMBL6884347 | 0.80 | KMT2A (0.35) | PPARAFFAR1TBXAS1BACE1KMT2A | |
| SCHEMBL7778151 | 0.77 | PPARA (0.32) | PPARABACE1 | |
| SCHEMBL6884341 | 0.73 | PPARA (0.35) | PPARAFFAR1TBXAS1DHFR | |
| SCHEMBL6156231 | 0.70 | MAOB (0.41) | BACE1KMT2A | |
| SCHEMBL6155830 | 0.69 | BACE1 (0.35) | TBXAS1BACE1 | |
| SCHEMBL6884295 | 0.69 | BACE1 (0.35) | TBXAS1BACE1 | |
| SCHEMBL6884293 | 0.69 | BACE1 (0.35) | TBXAS1BACE1 | |
| SCHEMBL6883517 | 0.68 | POLB (0.36) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |