Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155986 | 0.86 | PPARA (0.39) | PPARAFFAR1 | |
| SCHEMBL6884354 | 0.81 | TBXA2R (0.33) | PPARAFFAR1TBXAS1 | |
| SCHEMBL6884344 | 0.73 | PPARA (0.38) | PPARAFFAR1DHFRTBXAS1 | |
| SCHEMBL6886723 | 0.69 | MAOB (0.37) | — | |
| SCHEMBL6883521 | 0.67 | POLB (0.34) | — | |
| SCHEMBL3279984 | 0.66 | CYP4F2 (0.34) | PPARA | |
| SCHEMBL6158584 | 0.66 | VDR (0.34) | — | |
| SCHEMBL6886925 | 0.66 | VDR (0.34) | — | |
| SCHEMBL6155579 | 0.64 | VDR (0.35) | — | |
| SCHEMBL3279904 | 0.63 | VDR (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |