SCHEMBL6884392

SCHEMBL6884392

CC(C)(C)c1ccc2ccc3[c]ccc4ccc1c2c34

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28157336 0.81 ALDH1A1 (0.39) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL5746196 0.78 ALDH1A1 (0.55) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL5748360 0.78 ALDH1A1 (0.55) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL1046484 0.77 ALDH1A1 (0.33) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL578387 0.77 ALDH1A1 (0.33) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL2262927 0.74
SCHEMBL571692 0.74 ALDH1A1 (0.54) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL15351773 0.73 ALDH1A1 (0.31) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL5745446 0.72 NQO1 (0.36) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL5748614 0.72 MEN1 (0.34) ALDH1A1CYP3A4HPGDTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6824939-B2 PHOTORECEPTOR INCLUDING A PROTECTIVE LAYER INCLUDING A FILLER; PRODUCE HIGH QUALITY IMAGES FOR A LONG PERIOD OF TIME WITHOUT CAUSING DETERIORATION OF THE IMAGE RESOLUTION DUE TO SCATTERING OR DIFFUSE REFLECTION OF THE LASER LIGHT RICOH COMPANY LIMITED (JP) 2004-11-30 US disclosed
US-20030206226-A1 Electrophotographic image forming method and apparatus RICOH COMPANY LIMITED (JP) 2003-11-06 US disclosed