⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1719742 | 0.82 | LMNA (0.53) | — | |
| SCHEMBL15892733 | 0.82 | USP2 (0.41) | — | |
| SCHEMBL1049328 | 0.79 | — | — | |
| SCHEMBL15892716 | 0.78 | — | — | |
| SCHEMBL23892794 | 0.76 | — | — | |
| SCHEMBL10066792 | 0.76 | TDP1 (0.45) | — | |
| SCHEMBL18477598 | 0.76 | LMNA (0.40) | — | |
| SCHEMBL15724883 | 0.74 | LMNA (0.44) | — | |
| SCHEMBL19334217 | 0.74 | LMNA (0.38) | — | |
| SCHEMBL15892713 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9907854-B2 | Crosslinking reagents, macromolecules, therapeutic bioconjugates, and synthetic methods thereof | CellMosaic, Inc. (US) | 2018-03-06 | — | — | US | disclosed |
| US-20170065726-A1 | NOVEL CROSSLINKING REAGENTS, MACROMOLECULES, THERAPEUTIC BIOCONJUGATES, AND SYNTHETIC METHODS THEREOF | CELLMOSAIC INC (US) | 2017-03-09 | — | — | US | disclosed |
| US-9511150-B2 | Crosslinking reagents, macromolecules, therapeutic bioconjugates, and synthetic methods thereof | CellMosaic, Inc. (US) | 2016-12-06 | — | — | US | disclosed |
| US-8907079-B2 | Crosslinking reagents, macromolecules, therapeutic conjugates, and synthetic methods thereof | CELLMOSAIC INC. (US) | 2014-12-09 | — | — | US | disclosed |
| US-20140206903-A1 | NOVELCROSSLINKING REAGENTS, MACROMOLECULES, THERAPEUTIC CONJUGATES, AND SYNTHETIC METHODS THEREOF | CELLMOSAIC INC (US) | 2014-07-24 | — | — | US | disclosed |
| WO-2004081111-A1 | HIGH DIELECTRIC CONSTANT COMPOSITES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-09-23 | — | — | WO | disclosed |
| US-20040180988-A1 | High dielectric constant composites | BERNIUS MARK T (US) | 2004-09-16 | — | — | US | disclosed |