Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.40 |
| ▸ | ITGAV | P06756 | 8/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6883915 | 0.91 | ITGB3 (0.43) | ITGB3ITGAVITGA2BKMT2AMEN1 | |
| SCHEMBL6879633 | 0.91 | ITGB3 (0.35) | ITGB3ITGAVITGA2BKMT2AMEN1 | |
| Benzene SCHEMBL6882109 | 0.91 | MAPT (0.35) | ITGB3ITGAVITGA2BKMT2AMEN1 | |
| SCHEMBL6881843 | 0.90 | CHKA (0.37) | ITGB3ITGAVITGA2BKMT2AMEN1 | |
| SCHEMBL6884447 | 0.90 | ITGB3 (0.39) | ITGB3ITGAVITGA2BKMT2AMEN1 | |
| SCHEMBL6881760 | 0.89 | ITGB3 (0.43) | ITGB3ITGAVITGA2BLIMK2 | |
| SCHEMBL6883107 | 0.89 | ITGB3 (0.43) | ITGB3ITGAVITGA2BKMT2AMEN1 | |
| SCHEMBL6880511 | 0.89 | ITGAV (0.46) | ITGB3ITGAVITGA2BLMNA | |
| SCHEMBL6881029 | 0.88 | ITGB3 (0.47) | ITGB3ITGAVITGA2BKMT2AMEN1 | |
| SCHEMBL6881785 | 0.88 | ITGB3 (0.47) | ITGB3ITGAVITGA2BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747016-B1 | TREATING OSTEOPOROSIS IN WARM-BLOODED ANIMALS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-06-08 | — | — | US | disclosed |
| EP-1196416-B1 | SUBSTITUTED PURINE DERIVATIVES AS INHIBITORS OF CELL ADHESION | AVENTIS PHARMA GMBH (DE) | 2004-03-24 | — | — | EP | disclosed |
| EP-1196416-A1 | SUBSTITUTED PURINE DERIVATIVES AS INHIBITORS OF CELL ADHESION | Aventis Pharma Deutschland GmbH (DE) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001002399-A1 | SUBSTITUTED PURINE DERIVATIVES AS INHIBITORS OF CELL ADHESION | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-01-11 | — | — | WO | disclosed |
| EP-1065208-A1 | Substituted purine derivatives as inhibitors of cell adhesion | Aventis Pharma Deutschland GmbH (DE) | 2001-01-03 | — | — | EP | disclosed |