Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.54 |
| ▸ | CNR2 | P34972 | 8/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156319 | 0.84 | ESR1 (0.45) | CNR1CNR2TSHRCYP3A4HSD17B1 | |
| SCHEMBL4545013 | 0.83 | CNR1 (0.50) | CNR1CNR2TSHRKMT2A | |
| SCHEMBL2498564 | 0.82 | CYP3A4 (0.41) | CNR1CNR2CYP3A4HSD17B1HSD17B2 | |
| SCHEMBL10410114 | 0.82 | CNR1 (0.55) | CNR1CNR2TSHRCYP3A4KMT2A | |
| SCHEMBL10410407 | 0.81 | CNR1 (0.47) | CNR1CNR2TSHRMEN1KMT2A | |
| SCHEMBL23461954 | 0.81 | CNR2 (0.57) | CNR1CNR2 | |
| SCHEMBL10410260 | 0.80 | CNR1 (0.64) | CNR1CNR2 | |
| SCHEMBL23819732 | 0.79 | CNR2 (0.56) | CNR1CNR2 | |
| SCHEMBL10387238 | 0.79 | CNR1 (0.55) | CNR1CNR2TSHRKMT2A | |
| SCHEMBL10411338 | 0.79 | CNR1 (0.46) | CNR1CNR2TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |