Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | GRK5 | P34947 | 1/20 | 0.42 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | PRKX | P51817 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885186 | 0.84 | CNR1 (0.54) | CYP3A4KIF11HSD17B1HSD17B2TSHR | |
| SCHEMBL5753278 | 0.83 | FFAR4 (0.50) | ESR1ALDH1A1CYP3A4ESR2FFAR4 | |
| SCHEMBL4220480 | 0.81 | KIF11 (0.39) | ESR1ALDH1A1CYP3A4ESR2CHEK1 | |
| SCHEMBL5645169 | 0.80 | CNR1 (0.51) | ESR1ESR2KIF11CNR1CNR2 | |
| SCHEMBL10410125 | 0.80 | ESR1 (0.64) | ESR1ALDH1A1CYP3A4ESR2CHEK1 | |
| SCHEMBL4884889 | 0.80 | CNR1 (0.41) | ALDH1A1KIF11HSD17B1HSD17B2CNR1 | |
| SCHEMBL23461872 | 0.79 | CNR2 (0.47) | ESR1ALDH1A1CYP3A4ESR2CNR1 | |
| SCHEMBL3855592 | 0.79 | CNR2 (0.57) | CNR1CNR2 | |
| SCHEMBL17267375 | 0.78 | CYP2C19 (0.48) | ESR1ALDH1A1CYP3A4ESR2FFAR4 | |
| SCHEMBL10411503 | 0.78 | CHEK1 (0.49) | ESR1ALDH1A1CYP3A4ESR2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |