Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | KMO | O15229 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | MGAM | O43451 | 2/20 | 0.60 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.60 |
| ▸ | SI | P14410 | 2/20 | 0.60 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.60 |
| ▸ | SLC9A1 | P19634 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | APAF1 | O14727 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31714030 | 0.98 | EGLN3 (0.97) | EGLN3MAPTKDM4EKMORAB9A | |
| SCHEMBL9724438 | 0.88 | EGLN3 (0.78) | EGLN3MAPTKDM4ERAB9ANPC1 | |
| SCHEMBL3457145 | 0.85 | EGLN3 (0.74) | EGLN3MAPTKDM4ERAB9ANPC1 | |
| SCHEMBL361654 | 0.83 | GAA (0.73) | EGLN3RAB9ANPC1GAAMGAM | |
| SCHEMBL29625506 | 0.83 | GAA (0.73) | EGLN3RAB9ANPC1GAAMGAM | |
| SCHEMBL15149124 | 0.83 | EGLN3 (0.70) | EGLN3MAPTKDM4ERAB9ANPC1 | |
| SCHEMBL28801301 | 0.82 | RAB9A (0.81) | EGLN3MAPTKDM4ERAB9ANPC1 | |
| SCHEMBL29705990 | 0.82 | RAB9A (0.81) | EGLN3MAPTKDM4ERAB9ANPC1 | |
| SCHEMBL23880029 | 0.81 | EGLN3 (0.68) | EGLN3MAPTKDM4ERAB9ANPC1 | |
| SCHEMBL2490338 | 0.81 | KDM4E (1.00) | EGLN3MAPTKDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3266783-A1 | DERIVATIVES OF AZA ADAMANTANES AND USES THEREOF | Connexios Life Sciences Pvt. Ltd. (IN) | 2018-01-10 | — | — | EP | disclosed |
| EP-2794607-B1 | DERIVATIVES OF AZA ADAMANTANE AND USES THEREOF | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2017-05-10 | — | — | EP | disclosed |
| EP-2794607-B1 | DERIVATIVES OF AZA ADAMANTANE AND USES THEREOF | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2017-05-10 | — | — | EP | disclosed |
| EP-2800748-B1 | CYCLIC AMIDE DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE AND USES THEREOF | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2017-03-29 | — | — | EP | disclosed |
| EP-2800748-B1 | CYCLIC AMIDE DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE AND USES THEREOF | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2017-03-29 | — | — | EP | disclosed |
| US-9453014-B2 | Cyclic amide derivatives as inhibitors of 11-β-hydroxysteroid dehydrogenase and uses thereof | CONNEXIOS LIFE SCIENCES PVT. LTD. (IN) | 2016-09-27 | — | — | US | disclosed |
| US-9453014-B2 | Cyclic amide derivatives as inhibitors of 11-β-hydroxysteroid dehydrogenase and uses thereof | CONNEXIOS LIFE SCIENCES PVT. LTD. (IN) | 2016-09-27 | — | — | US | disclosed |
| US-9453014-B2 | Cyclic amide derivatives as inhibitors of 11-β-hydroxysteroid dehydrogenase and uses thereof | CONNEXIOS LIFE SCIENCES PVT. LTD. (IN) | 2016-09-27 | — | — | US | disclosed |
| US-9303016-B2 | Derivatives of aza adamantane and uses thereof | CONNEXIOS LIFE SCIENCES PVT. LTD. (IN) | 2016-04-05 | — | — | US | disclosed |
| US-9303016-B2 | Derivatives of aza adamantane and uses thereof | CONNEXIOS LIFE SCIENCES PVT. LTD. (IN) | 2016-04-05 | — | — | US | disclosed |
| WO-2013128465-A1 | CYCLIC AMIDE DERIVATIVES AS INHIBITORS OF 11 - BETA - HYDROXYSTEROID DEHYDROGENASE AND USES THEREOF | CONNEXIOS LIFE SCIENCES PVT. LTD. (IN) | 2013-09-06 | — | — | WO | disclosed |
| WO-2013111150-A1 | DERIVATIVES OF AZA ADAMANTANE AND USES THEREOF | CONNEXIOS LIFE SCIENCES PVT. LTD. (IN) | 2013-08-01 | — | — | WO | disclosed |
| WO-2013111150-A1 | DERIVATIVES OF AZA ADAMANTANE AND USES THEREOF | CONNEXIOS LIFE SCIENCES PVT. LTD. (IN) | 2013-08-01 | — | — | WO | disclosed |
| US-20090239380-A1 | POLISHING LIQUID FOR METAL AND POLISHING METHOD USING THE SAME | FUJIFILM CORPORATION (JP) | 2009-09-24 | — | — | US | disclosed |
| US-20090239380-A1 | POLISHING LIQUID FOR METAL AND POLISHING METHOD USING THE SAME | FUJIFILM CORPORATION (JP) | 2009-09-24 | — | — | US | disclosed |
| US-20040082079-A1 | Low affinity screening method | GRAFFINITY PHARMACEUTICALS AG. (DE) | 2004-04-29 | — | — | US | disclosed |
| EP-1360489-A1 | LOW AFFINITY SCREENING METHOD | Graffinity Pharmaceuticals Aktiengesellschaft (DE) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002063299-A1 | LOW AFFINITY SCREENING METHOD | GRAFFINITY PHARMACEUTICALS AG (DE) | 2002-08-15 | — | — | WO | disclosed |
| US-5602196-A | OXIDATION AND HEAT RESISTANCE; PHOTOSTABILITY | CIBA-GEIGY CORPORATION (US) | 1997-02-11 | — | — | US | disclosed |
| EP-0716076-A2 | Bisphenolester derivatives | CIBA-GEIGY AG (CH) | 1996-06-12 | — | — | EP | disclosed |