Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.52 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.52 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6093565 | 0.77 | KCNE1 (0.49) | ERCC1FEN1ERCC4SMN1; SMN2KCNH2 | |
| SCHEMBL12471730 | 0.74 | ERCC1 (0.63) | ERCC1FEN1ERCC4SMN1; SMN2 | |
| SCHEMBL15456497 | 0.73 | ERCC1 (0.54) | ERCC1FEN1ERCC4 | |
| SCHEMBL6644944 | 0.73 | ERCC1 (0.49) | ERCC1FEN1ERCC4KCNH2 | |
| SCHEMBL15456406 | 0.73 | ERCC1 (0.56) | ERCC1FEN1ERCC4 | |
| SCHEMBL13218323 | 0.72 | ERCC1 (0.60) | ERCC1FEN1ERCC4SMN1; SMN2 | |
| SCHEMBL5113949 | 0.72 | SMN1; SMN2 (0.45) | ERCC1FEN1ERCC4PRKAA2SMN1; SMN2 | |
| SCHEMBL5313308 | 0.72 | ERCC1 (0.60) | ERCC1FEN1ERCC4SMN1; SMN2 | |
| SCHEMBL6645479 | 0.72 | ERCC1 (0.46) | ERCC1FEN1ERCC4SMN1; SMN2KCNH2 | |
| SCHEMBL4392827 | 0.71 | KCNH2 (0.50) | ERCC1FEN1ERCC4SMN1; SMN2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004062613-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-07-29 | — | — | WO | disclosed |