Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 10/20 | 0.38 |
| ▸ | LGMN | Q99538 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886852 | 0.95 | PTGFR (0.56) | PTGFRHSD11B1MMP2MMP9 | |
| SCHEMBL6887275 | 0.93 | PTGFR (0.57) | PTGFRHSD11B1LGMNPAX8DPP4 | |
| SCHEMBL6884600 | 0.88 | PTGFR (0.46) | PTGFRHSD11B1LGMNPAX8MMP1 | |
| SCHEMBL3384707 | 0.86 | PTGFR (0.51) | PTGFRHSD11B1PAX8ALDH1A1 | |
| SCHEMBL3385965 | 0.83 | PTGFR (0.49) | PTGFRHSD11B1PAX8ALDH1A1 | |
| SCHEMBL3383972 | 0.83 | PTGFR (0.72) | PTGFRHSD11B1LGMNPAX8DPP4 | |
| SCHEMBL3383792 | 0.82 | PTGFR (0.58) | PTGFRHSD11B1MMP1MMP2MMP3 | |
| SCHEMBL13005135 | 0.82 | PTGFR (0.58) | PTGFRHSD11B1MMP1MMP2MMP3 | |
| SCHEMBL7047521 | 0.82 | PTGFR (0.58) | PTGFRHSD11B1MMP1MMP2MMP3 | |
| SCHEMBL3384874 | 0.80 | PTGFR (0.59) | PTGFRHSD11B1PAX8MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487442-A1 | THIAZOLIDINE CARBOXAMIDE DERIVATIVES AS MODULATORS OF THE PROSTAGLANDIN F RECEPTOR | Applied Research Systems ARS Holding N.V. (AN) | 2004-12-22 | — | — | EP | claimed |
| WO-2003082278-A1 | THIAZOLIDINE CARBOXAMIDE DERIVATIVES AS MODULATORS OF THE PROSTAGLANDIN F RECEPTOR | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-10-09 | — | — | WO | claimed |