Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 10/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3383893 | 0.93 | PTGFR (0.56) | PTGFRHSD11B1ALDH1A1POLB | |
| SCHEMBL3386001 | 0.91 | PTGFR (0.55) | PTGFRHSD11B1GRIA4ATMALDH1A1 | |
| SCHEMBL3384707 | 0.91 | PTGFR (0.51) | PTGFRHSD11B1GRIA4ATMALDH1A1 | |
| SCHEMBL13005135 | 0.85 | PTGFR (0.58) | PTGFRHSD11B1ALDH1A1 | |
| SCHEMBL3383792 | 0.85 | PTGFR (0.58) | PTGFRHSD11B1ALDH1A1 | |
| SCHEMBL7047521 | 0.85 | PTGFR (0.58) | PTGFRHSD11B1ALDH1A1 | |
| SCHEMBL3384874 | 0.84 | PTGFR (0.59) | PTGFRHSD11B1GRIA4ATMALDH1A1 | |
| SCHEMBL3413748 | 0.84 | PTGFR (0.44) | PTGFRHSD11B1ATMALDH1A1POLB | |
| SCHEMBL6885482 | 0.83 | PTGFR (0.51) | PTGFRHSD11B1ALDH1A1PAX8 | |
| SCHEMBL3383972 | 0.83 | PTGFR (0.72) | PTGFRHSD11B1GRIA4PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487442-B1 | THIAZOLIDINE CARBOXAMIDE DERIVATIVES AS MODULATORS OF THE PROSTAGLANDIN F RECEPTOR | MERCK SERONO SA (CH) | 2010-12-01 | — | — | EP | claimed |
| EP-1487442-A1 | THIAZOLIDINE CARBOXAMIDE DERIVATIVES AS MODULATORS OF THE PROSTAGLANDIN F RECEPTOR | Applied Research Systems ARS Holding N.V. (AN) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003082278-A1 | THIAZOLIDINE CARBOXAMIDE DERIVATIVES AS MODULATORS OF THE PROSTAGLANDIN F RECEPTOR | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-10-09 | — | — | WO | disclosed |