Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 3/20 | 0.65 |
| ▸ | EIF2AK3 | Q9NZJ5 | 5/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.52 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.52 |
| ▸ | IGF1R | P08069 | 1/20 | 0.52 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 2/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.51 |
| ▸ | HCK | P08631 | 2/20 | 0.51 |
| ▸ | PLK4 | O00444 | 1/20 | 0.51 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | PAK4 | O96013 | 1/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.51 |
| ▸ | INSR | P06213 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878984 | 0.94 | TEK (0.62) | TEKEIF2AK3EGFRERBB2ERBB4 | |
| Benzenesulfonamide SCHEMBL6459329 | 0.88 | TEK (0.65) | TEKEIF2AK3EGFRERBB2ERBB4 | |
| SCHEMBL6878546 | 0.87 | EIF2AK3 (0.68) | TEKEIF2AK3EGFRERBB2ERBB4 | |
| SCHEMBL6876636 | 0.84 | TEK (0.60) | TEKEIF2AK3EGFRERBB2ERBB4 | |
| SCHEMBL6460184 | 0.84 | TEK (0.67) | TEKEIF2AK3EGFRERBB2ERBB4 | |
| SCHEMBL6465261 | 0.83 | TEK (0.66) | TEKEIF2AK3EGFRERBB2ERBB4 | |
| SCHEMBL6459888 | 0.83 | TEK (0.72) | TEKEIF2AK3EGFRERBB2ERBB4 | |
| SCHEMBL6462812 | 0.83 | TEK (0.70) | TEKEIF2AK3EGFRERBB2ERBB4 | |
| SCHEMBL6462087 | 0.83 | TEK (0.67) | TEKEIF2AK3EGFRERBB2ERBB4 | |
| SCHEMBL6464132 | 0.83 | TEK (0.67) | TEKEIF2AK3EGFRERBB2ERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004100868-A2 | METHOD OF TREATING TRANSPLANT REJECTION | ABBOTT LABORATORIES (US) | 2004-11-25 | — | — | WO | disclosed |