Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22702325 | 1.00 | KMT2A (0.34) | KMT2AMEN1PABPC1ADRA2CBRD4 | |
| SCHEMBL82278 | 0.77 | — | — | |
| SCHEMBL12648597 | 0.77 | — | — | |
| SCHEMBL12648729 | 0.77 | — | — | |
| SCHEMBL13887700 | 0.76 | — | — | |
| SCHEMBL24391218 | 0.73 | MAPT (0.36) | KMT2AMEN1PABPC1 | |
| SCHEMBL17433533 | 0.71 | BRD4 (0.36) | KMT2AMEN1PABPC1BRD4 | |
| SCHEMBL17435217 | 0.71 | BRD4 (0.39) | KMT2AMEN1PABPC1BRD4 | |
| SCHEMBL23451088 | 0.70 | P2RX7 (0.31) | — | |
| SCHEMBL11886630 | 0.70 | BRD4 (0.31) | KMT2ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408037-A1 | Novel diarylmethylpiperazine and diarylmethylphenyl compounds with analgesic effect | AstraZeneca AB (SE) | 2004-04-14 | — | — | EP | disclosed |
| US-6680321-B1 | 4-((1-PIPERAZINYLMETHYL)-BENZAMIDE DERIVATIVES; HYPOTENSIVE AGENTS; IMMUNOMODULATORS | ASTRAZENECA CANADA, INC. (CA) | 2004-01-20 | — | — | US | disclosed |
| EP-0915855-A1 | NOVEL COMPOUNDS WITH ANALGESIC EFFECT | Astra Pharma Inc. (CA) | 1999-05-19 | — | — | EP | disclosed |