Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 12/20 | 0.35 |
| ▸ | CA2 | P00918 | 12/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 6/20 | 0.32 |
| ▸ | CA9 | Q16790 | 6/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.32 |
| ▸ | PDE5A | O76074 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL788634 | 0.81 | TSHR (0.46) | CA1CA2TSHRGSK3BCA12 | |
| SCHEMBL7030562 | 0.81 | TSHR (0.46) | CA1CA2TSHRGSK3BCA12 | |
| SCHEMBL11289015 | 0.81 | TSHR (0.46) | CA1CA2TSHRGSK3BCA12 | |
| SCHEMBL38256 | 0.81 | TSHR (0.46) | CA1CA2TSHRGSK3BCA12 | |
| SCHEMBL7198908 | 0.81 | TSHR (0.46) | CA1CA2TSHRGSK3BCA12 | |
| SCHEMBL375915 | 0.81 | TSHR (0.46) | CA1CA2TSHRGSK3BCA12 | |
| SCHEMBL4704343 | 0.81 | TSHR (0.46) | CA1CA2TSHRGSK3BCA12 | |
| SCHEMBL4278638 | 0.81 | TSHR (0.46) | CA1CA2TSHRGSK3BCA12 | |
| SCHEMBL319584 | 0.81 | TSHR (0.46) | CA1CA2TSHRGSK3BCA12 | |
| SCHEMBL8711595 | 0.81 | TSHR (0.46) | CA1CA2TSHRGSK3BCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411954-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | Pharmasset Limited (BB) | 2004-04-28 | — | — | EP | disclosed |
| WO-2002032920-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | PHARMASSET LIMITED (BB) | 2002-04-25 | — | — | WO | disclosed |