Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.79 |
| ▸ | GAA | P10253 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | NMT1 | P30419 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885764 | 1.00 | ALDH1A1 (0.79) | ALDH1A1GAAHPGDNMT1MAPT | |
| SCHEMBL28100786 | 0.84 | ALDH1A1 (0.58) | ALDH1A1GAAHPGDMAPTPKM | |
| SCHEMBL9354265 | 0.81 | ALDH1A1 (0.64) | ALDH1A1GAAHPGDNMT1MAPT | |
| SCHEMBL9354277 | 0.81 | ALDH1A1 (0.64) | ALDH1A1GAAHPGDNMT1MAPT | |
| SCHEMBL7825460 | 0.79 | NMT1 (0.68) | ALDH1A1GAAHPGDNMT1MAPT | |
| SCHEMBL11141342 | 0.79 | NMT1 (0.68) | ALDH1A1GAAHPGDNMT1MAPT | |
| SCHEMBL11141344 | 0.79 | NMT1 (0.68) | ALDH1A1GAAHPGDNMT1MAPT | |
| SCHEMBL7825464 | 0.79 | NMT1 (0.68) | ALDH1A1GAAHPGDNMT1MAPT | |
| SCHEMBL6455411 | 0.79 | ALDH1A1 (0.57) | ALDH1A1GAAHPGDMAPTLMNA | |
| SCHEMBL15709020 | 0.78 | ALDH1A1 (0.78) | ALDH1A1GAAHPGDNMT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082079-A1 | Low affinity screening method | GRAFFINITY PHARMACEUTICALS AG. (DE) | 2004-04-29 | — | — | US | disclosed |
| EP-1360489-A1 | LOW AFFINITY SCREENING METHOD | Graffinity Pharmaceuticals Aktiengesellschaft (DE) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002063299-A1 | LOW AFFINITY SCREENING METHOD | GRAFFINITY PHARMACEUTICALS AG (DE) | 2002-08-15 | — | — | WO | disclosed |
| US-3948942-A | PLANT FUNGICIDES | PEPRO, SOCIETE POUR LE DEVELOPMENT ET LA VENTE DE SPECIALITIES CHIMIQUES (FR) | 1976-04-06 | — | — | US | disclosed |