Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | STAT1 | P42224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312703 | 0.87 | TSHR (0.38) | CHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL12907335 | 0.80 | CYP11B1 (0.37) | CYP2C19HIF1ACYP11B1CYP11B2CHRM2 | |
| SCHEMBL7377819 | 0.75 | CYP11B1 (0.37) | CYP2C19HIF1ACYP11B1CYP11B2CHRM2 | |
| SCHEMBL9588293 | 0.74 | CYP11B1 (0.34) | CYP11B1CYP11B2 | |
| SCHEMBL7534704 | 0.72 | HIF1A (0.37) | CYP2C19HIF1APTGDR2KDM4EALDH1A1 | |
| SCHEMBL923644 | 0.72 | LMNA (0.37) | CYP11B1CYP11B2KDM4EMAPTALDH1A1 | |
| SCHEMBL14197521 | 0.71 | KDM4C (0.36) | ALDH1A1 | |
| SCHEMBL1423832 | 0.71 | TSHR (0.44) | CYP2C19MAPTALDH1A1HPGD | |
| SCHEMBL1312709 | 0.70 | SIRT2 (0.39) | CYP11B1CYP11B2GABBR2GABBR1 | |
| SCHEMBL30946779 | 0.70 | BRD4 (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471056-A1 | PROCESS FOR PRODUCING FUSED IMIDAZOLE COMPOUND, REFORMATSKY REAGENT IN STABLE FORM, AND PROCESS FOR PRODUCING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2004-10-27 | — | — | EP | disclosed |