Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2919242 | 0.87 | ESR1 (0.33) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL2917802 | 0.87 | ESR1 (0.33) | ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL8972492 | 0.85 | ESR1 (0.41) | ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL12979079 | 0.85 | ESR1 (0.41) | ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL4620122 | 0.85 | ESR1 (0.32) | ESR1ESR2 | |
| SCHEMBL11716671 | 0.85 | ESR1 (0.32) | ESR1ESR2 | |
| SCHEMBL9342089 | 0.85 | ESR1 (0.41) | ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL4619555 | 0.85 | ESR1 (0.46) | ESR1ESR2CA1CA2CA9 | |
| SCHEMBL9563020 | 0.83 | ESR1 (0.45) | ESR1ESR2CA1CA2CA9 | |
| SCHEMBL9563048 | 0.83 | ESR1 (0.45) | ESR1ESR2CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884879-B2 | Method of synthesizing siloxane monomers and use thereof | SILECS OY (FI) | 2018-02-06 | — | — | US | claimed |
| CN-106866722-A | A kind of organo-silicon compound containing benzocyclobutene functionalization and preparation method thereof | 复旦大学 | 2017-06-20 | — | — | CN | claimed |
| US-20170088565-A1 | Method of synthesizing siloxane monomers and use thereof | SILECS OY (FI) | 2017-03-30 | — | — | US | claimed |
| US-20140249326-A1 | Method of Synthesizing Siloxane Monomers and Use Thereof | SILECS OY (FI) | 2014-09-04 | — | — | US | claimed |
| WO-2012172176-A9 | METHOD OF SYNTHESIZING SILOXANE MONOMERS AND USE THEREOF | SILECS OY (FI) | 2013-02-07 | — | — | WO | claimed |
| WO-2012172176-A2 | METHOD OF SYNTHESIZING SILOXANE MONOMERS AND USE THEREOF | SILECS OY (FI) | 2012-12-20 | — | — | WO | claimed |
| EP-0721474-B1 | CATALYST SYSTEM FOR THE POLYMERIZATION OF ETHYLENE | DSM NV (NL) | 1998-12-09 | — | — | EP | claimed |
| US-5777050-A | Process for polymerizing ethylene in the presence of a catalyst composition | DSM N.V. (NL) | 1998-07-07 | — | — | US | claimed |
| EP-0594175-B1 | Process for producing aromatic polycarbonate | MITSUBISHI CHEM CORP (JP) | 1997-06-18 | — | — | EP | claimed |
| EP-0721474-A1 | CATALYST SYSTEM FOR THE POLYMERIZATION OF ETHYLENE | DSM N.V. (NL) | 1996-07-17 | — | — | EP | claimed |
| WO-1995009191-A1 | CATALYST SYSTEM FOR THE POLYMERIZATION OF ETHYLENE | DSM N.V. (NL) | 1995-04-06 | — | — | WO | claimed |
| US-5391691-A | Melt condensing am aromatic diol compound and a carbonic acid diester in the presence of an interesterification catalyst and co-presence of an organosilicon compound | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1995-02-21 | — | — | US | claimed |
| EP-0594175-A1 | Process for producing aromatic polycarbonate | MITSUBISHI CHEMICAL CORPORATION (JP) | 1994-04-27 | — | — | EP | claimed |
| EP-0156209-B1 | SILICONE FLAME RETARDANTS FOR NYLON | GENERAL ELECTRIC COMPANY (US) | 1991-07-24 | — | — | EP | claimed |
| EP-0156209-A2 | Silicone flame retardants for nylon | GENERAL ELECTRIC COMPANY (US) | 1985-10-02 | — | — | EP | claimed |
| US-4496680-A | CARBOXYLIC ACID METAL SALT, ALUMINUM TRIAZYDRATE, ORGANIC HILIDE | GENERAL ELECTRIC COMPANY (US) | 1985-01-29 | — | — | US | claimed |
| US-11572434-B2 | Curable composition, method for producing same, and article using same | DAIKIN INDUSTRIES, LTD. (JP) | 2023-02-07 | — | — | US | disclosed |
| CN-113583179-B | Composition for preparing polarizing film, preparation method of polarizing film, polarizing film and display module | TCL华星光电技术有限公司 | 2022-11-25 | — | — | CN | disclosed |
| US-4065482-A | Siloxanediolate complexes and preparation thereof | GENERAL ELECTRIC COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4003917-A | Siloxanediolate complexes and preparation thereof | GENERAL ELECTRIC COMPANY (US) | 1977-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088565-A1 | Method of synthesizing siloxane monomers and use thereof | MSMO1, PCNA, PIEZO1 | ESR1 1734/4885ESR2 2662/4885CA1 1111/4885 |
| US-20140249326-A1 | Method of Synthesizing Siloxane Monomers and Use Thereof | MSMO1, PCNA, PIEZO1 | ESR1 1734/4885ESR2 2662/4885CA1 1111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.