Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | ESR1 | P03372 | 2/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | JAK2 | O60674 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689904 | 1.00 | MAPT (0.60) | MAPTKDM4EHSD17B10HPGDESR1 | |
| SCHEMBL688593 | 1.00 | MAPT (0.60) | MAPTKDM4EHSD17B10HPGDESR1 | |
| SCHEMBL27705566 | 0.92 | MAPT (0.58) | MAPTKDM4EHSD17B10HPGDESR1 | |
| SCHEMBL27686601 | 0.92 | MAPT (0.58) | MAPTKDM4EHSD17B10HPGDESR1 | |
| SCHEMBL5176447 | 0.88 | ESR1 (0.49) | MAPTKDM4EHSD17B10HPGDESR1 | |
| SCHEMBL5176455 | 0.88 | ESR1 (0.49) | MAPTKDM4EHSD17B10HPGDESR1 | |
| SCHEMBL8719130 | 0.85 | NFKB1 (0.59) | MAPTKDM4EHSD17B10HPGDESR1 | |
| SCHEMBL28994291 | 0.85 | ESR1 (0.75) | MAPTKDM4EHSD17B10HPGDESR1 | |
| SCHEMBL8445240 | 0.85 | TSHR (0.47) | MAPTKDM4EHSD17B10HPGDESR1 | |
| SCHEMBL1918661 | 0.85 | GAA (0.47) | MAPTKDM4EHSD17B10HPGDESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9464183-B2 | Rubber composition and pneumatic tire using the same | BRIDGESTONE CORPORATION (JP) | 2016-10-11 | — | — | US | disclosed |
| EP-1820667-B1 | PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2012-02-29 | — | — | EP | disclosed |
| CN-101076457-B | Pneumatic tire | BRIDGESTONE CORP | 2011-07-27 | — | — | CN | disclosed |
| EP-1724302-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRE USING SAME | BRIDGESTONE CORP (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-20110146886-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE USING THE SAME | BRIDGESTONE CORPORATION (JP) | 2011-06-23 | — | — | US | disclosed |
| US-7823614-B2 | Pneumatic tire | BRIDGESTONE CORPORATION (JP) | 2010-11-02 | — | — | US | disclosed |
| US-20090229728-A1 | PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| US-7491840-B2 | Compound and composition containing the same | MITSUI CHEMICALS, INC. (JP) | 2009-02-17 | — | — | US | disclosed |
| US-20080047650-A1 | Rubber Composition And Pneumatic Tire Using The Same | BRIDGESTONE CORPORATION (JP) | 2008-02-28 | — | — | US | disclosed |
| CN-101076457-A | Pneumatic tire | BRIDGESTONE CORP (JP) | 2007-11-21 | — | — | CN | disclosed |
| EP-1820667-A1 | PNEUMATIC TIRE | Bridgestone Corporation (JP) | 2007-08-22 | — | — | EP | disclosed |
| EP-1724252-A1 | COMPOUND AND COMPOSITION CONTAINING THE SAME | Mitsui Chemicals, Inc. (JP) | 2006-11-22 | — | — | EP | disclosed |
| EP-1724302-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE USING SAME | Bridgestone Corporation (JP) | 2006-11-22 | — | — | EP | disclosed |
| US-20060205971-A1 | Compound and composition containing the same | MITSUI CHEMICALS, INC. (JP) | 2006-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205971-A1 | Compound and composition containing the same | RFC4, RFC5, RFC1 | MAPT 1024/4885KDM4E 2085/4885HSD17B10 2487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.