SCHEMBL6886429

SCHEMBL6886429

C=CCc1c[nH]c(=O)nc1N[C@@H]1O[C@H](CO)[C@H](OS(C)(=O)=O)[C@H]1O

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6887384 0.90 GSK3B (0.36) GSK3B
SCHEMBL6887576 0.87 GSK3B (0.34) GSK3B
SCHEMBL6884989 0.85 GSK3B (0.36) GSK3B
SCHEMBL6885088 0.85 GSK3B (0.36) GSK3B
SCHEMBL6889230 0.84 GSK3B (0.43) GSK3B
SCHEMBL6886914 0.84 SLC5A2 (0.38) GSK3B
SCHEMBL6885551 0.84 GSK3B (0.36) GSK3B
SCHEMBL6884015 0.82 GSK3B (0.35) GSK3B
SCHEMBL6884779 0.82 GSK3B (0.33) GSK3B
SCHEMBL6887257 0.82 GSK3B (0.33) GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1411954-A2 MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION Pharmasset Limited (BB) 2004-04-28 EP disclosed
WO-2002032920-A2 MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION PHARMASSET LIMITED (BB) 2002-04-25 WO disclosed