Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAT1 | P18440 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8198993 | 0.82 | NAT1 (0.69) | NAT1MEN1KMT2AALDH1A1HSD17B3 | |
| SCHEMBL7246592 | 0.82 | NAT1 (0.69) | NAT1MEN1KMT2AALDH1A1HSD17B3 | |
| SCHEMBL7246589 | 0.82 | NAT1 (0.69) | NAT1MEN1KMT2AALDH1A1HSD17B3 | |
| SCHEMBL8179956 | 0.77 | PTGS2 (0.69) | NAT1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL8179957 | 0.77 | PTGS2 (0.69) | NAT1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL8710472 | 0.74 | HSD17B3 (0.70) | NAT1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL8710470 | 0.74 | HSD17B3 (0.70) | NAT1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL8492533 | 0.72 | PTGS2 (0.51) | MEN1KMT2A | |
| SCHEMBL9429106 | 0.69 | NAT1 (0.51) | NAT1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL9429104 | 0.69 | NAT1 (0.51) | NAT1MEN1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673816-B1 | Rhodanine carboxylic acid derivatives for the treatment and prevention of metabolic bone disorders | Esswein, Angelika (DE) | 2004-01-06 | — | — | US | disclosed |