Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31188053 | 1.00 | CES2 (0.48) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL11291116 | 1.00 | CES2 (0.48) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL11299658 | 1.00 | CES2 (0.48) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL10719339 | 1.00 | CES2 (0.48) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL1649117 | 1.00 | CES2 (0.48) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL20030126 | 1.00 | CES2 (0.48) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL11299179 | 1.00 | CES2 (0.48) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL11765183 | 1.00 | CES2 (0.48) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL19426062 | 1.00 | CES2 (0.48) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL4682213 | 1.00 | CES2 (0.48) | CES2CES1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869937-A4 | NOVEL AMIDE-BASED CATIONIC LIPIDS | PROMEGA BIOSCIENCES INC (US) | 2004-07-21 | — | — | EP | disclosed |
| US-6638529-B2 | Lipid copound for use in the transfer macromolecules in cells | GENTA INCORPORATED | 2003-10-28 | — | — | US | disclosed |
| US-20020156237-A1 | Novel amide-based cationic lipids | PROMEGA BIOSCIENCES, INC. | 2002-10-24 | — | — | US | disclosed |
| US-6339173-B1 | FOR INTERFERING WITH PROTEIN EXPRESSION IN A CELL; USEFUL IN LIPID AGGREGATES FOR THE DELIVERY OF MACROMOLECULES INTO CELLS | PROMEGA BIOSCIENCES, INC. | 2002-01-15 | — | — | US | disclosed |
| US-6020526-A | Amide-based cationic lipids | GENTA, INCORPORATED (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0869937-A1 | NOVEL AMIDE-BASED CATIONIC LIPIDS | GENTA INCORPORATED (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997003939-A9 | NOVEL AMIDE-BASED CATIONIC LIPIDS | — | 1997-05-22 | — | — | WO | disclosed |
| WO-1997003939-A1 | NOVEL AMIDE-BASED CATIONIC LIPIDS | GENTA INCORPORATED (US) | 1997-02-06 | — | — | WO | disclosed |
| EP-0014232-B1 | POLYPHOSPHAZENE POLYMERS CONTAINING SUBSTITUENTS DERIVED FROM KETOXIMES AND PROCESS FOR PRODUCING THEM | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1982-12-15 | — | — | EP | disclosed |
| EP-0014232-A1 | Polyphosphazene polymers containing substituents derived from ketoximes and process for producing them | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-08-20 | — | — | EP | disclosed |
| US-4179556-A | Polyphosphazene polymers containing substituents derived from ketoximes | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156237-A1 | Novel amide-based cationic lipids | CETP, SGMS1, CERT1 | CES2 2385/4885CES1 152/4885GPR84 1152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.