SCHEMBL6886925

SCHEMBL6886925

CC(=CC=CC(C)(C)O)c1cccc(CCc2ccc(C(O[SiH](C)C)C(C)(C)C)c(C(O[SiH](C)C)C(C)(C)C)c2)c1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
VDR P11473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6158584 1.00 VDR (0.34) VDR
SCHEMBL6887848 0.92 VDR (0.35) VDR
SCHEMBL6155579 0.92 VDR (0.35) VDR
SCHEMBL6883395 0.87 VDR (0.41) VDR
SCHEMBL6885668 0.87 MRGPRX4 (0.35) VDR
SCHEMBL6156246 0.87 MRGPRX4 (0.35) VDR
SCHEMBL6155753 0.87 VDR (0.41) VDR
SCHEMBL6884303 0.87 SLC7A5 (0.32)
SCHEMBL6885229 0.83
SCHEMBL6885244 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 US disclosed