SCHEMBL6887037

SCHEMBL6887037

N=C(N)NCCCC(NC(=O)C(CCC(=O)O)NC(=O)C(Cc1ccccc1)NC(=O)C(N)CCCCN)C(=O)NC(CCC(N)=O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 10/20 0.54
▸ NPY1R P25929 5/20 0.54
▸ NPY2R P49146 4/20 0.54
▸ NPY5R Q15761 4/20 0.54
▸ FOLH1 Q04609 2/20 0.51
▸ OPRM1 P35372 1/20 0.51
▸ MMP2 P08253 1/20 0.48
▸ TFPI P10646 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6887041 1.00 NPY4R (0.54) NPY4RNPY1RNPY2RNPY5RFOLH1
SCHEMBL31356561 0.97 NPY4R (0.56) NPY4RNPY1RNPY2RNPY5RFOLH1
SCHEMBL30958066 0.97 NPY4R (0.56) NPY4RNPY1RNPY2RNPY5RFOLH1
SCHEMBL31190176 0.94 NPY4R (0.54) NPY4RNPY1RNPY2RNPY5RFOLH1
SCHEMBL30375565 0.93 NPY4R (0.61) NPY4RNPY1RNPY2RNPY5RMMP2
SCHEMBL29630650 0.93 NPY4R (0.61) NPY4RNPY1RNPY2RNPY5RMMP2
SCHEMBL30359264 0.93 NPY4R (0.61) NPY4RNPY1RNPY2RNPY5RMMP2
SCHEMBL30903447 0.93 NPY4R (0.58) NPY4RNPY1RNPY2RNPY5RFOLH1
SCHEMBL30958097 0.92 NPY4R (0.59) NPY4RNPY1RNPY2RNPY5RMMP2
SCHEMBL30958098 0.92 NPY4R (0.59) NPY4RNPY1RNPY2RNPY5RMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0636028-B1 SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING AN AMPHIPHATIC CATIONIC PEPTIDE UNIV CALIFORNIA (US) 2004-03-03 — — EP disclosed
EP-0708637-B1 SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING DENDRIMER POLYCATIONS UNIV CALIFORNIA (US) 2004-01-28 — — EP disclosed
EP-1236473-A2 Self-assembling polynucleotide delivery system THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2002-09-04 — — EP disclosed
US-6113946-A EUKARYOTIC CELL, POLYNUCLEOTIDE AND DENDRIMER POLYCATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-09-05 — — US disclosed
EP-0636028-A4 SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM. UNIV CALIFORNIA (US) 1998-12-09 — — EP disclosed
EP-0708637-A4 SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING DENDRIMER POLYCATIONS UNIV CALIFORNIA (US) 1998-08-12 — — EP disclosed
CN-1178797-A Oligopeptide derivative containing alpha, gamma-diaminobutanoic acid HOFFMANN LA ROCHE (CH) 1998-04-15 — — CN disclosed
EP-0834572-A2 Alpha, gamma-diaminobutyric acid (DAB) containing oligopeptide derivatives F. HOFFMANN-LA ROCHE AG (CH) 1998-04-08 — — EP disclosed
EP-0656747-A4 COMPOSITION AND METHOD FOR ALTERING DNA SEQUENCES BY HOMOLOGOUS RECOMBINATION. UNIV CALIFORNIA (US) 1997-05-07 — — EP disclosed
EP-0708637-A1 SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING DENDRIMER POLYCATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-05-01 — — EP disclosed
EP-0656747-A1 COMPOSITION AND METHOD FOR ALTERING DNA SEQUENCES BY HOMOLOGOUS RECOMBINATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-06-14 — — EP disclosed
EP-0636028-A1 SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-02-01 — — EP disclosed
WO-1995002397-A1 SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING DENDRIMER POLYCATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-01-26 — — WO disclosed
WO-1994004032-A1 COMPOSITION AND METHOD FOR ALTERING DNA SEQUENCES BY HOMOLOGOUS RECOMBINATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-03-03 — — WO disclosed
WO-1993019768-A1 SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1993-10-14 — — WO disclosed
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